Pellino 1 Antikörper (N-Term)

Produktnummer ABIN2787222

Der Kaninchen Polyklonal anti-Pellino 1 Antikörper (ABIN2787222) detektiert spezifisch Pellino 1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für Pellino 1 Antikörper (N-Term) (ABIN2787222)

Target: Pellino 1 (PELI1) (Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Pellino 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Pellino 1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: PELI1 Antibody - N-terminal region

Sequenz: ESPIDFVVTD TVPGSQSNSD TQSVQSTISR FACRIICERN PPFTARIYAA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PELI1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PELI1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57429-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Pellino 1

Target: Pellino 1 (PELI1) (Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))

Andere Bezeichnung: PELI1

Hintergrund:

Background Information: PELI1 is an scaffold protein involved in the IL-1 signaling pathway via its interaction with the complex containing IRAK kinases and TRAF6. PELI1 is required for NF-kappa-B activation and IL-8 gene expression in response to IL-1.

Gene Name: Pellino E3 ubiquitin protein ligase 1

Alternative Symbols: DKFZp686C18116, MGC50990

Protein Name: E3 ubiquitin-protein ligase pellino homolog 1

Molekulargewicht: 46kDa

Gen-ID: 57162

NCBI Accession: NP_065702

UniProt: Q8C669

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades