CDCA7L Antikörper (Middle Region)
Kurzübersicht für CDCA7L Antikörper (Middle Region) (ABIN2787158)
Target
Alle CDCA7L Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Verwendungszweck
- CDCA7L Antibody - middle region
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Sequenz
- PPCRGICNCS YCRKRDGRCA TGILIHLAKF YGYDNVKEYL ESLQKELVED
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Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Yeast: 90%, Zebrafish: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CDCA7L. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CDCA7L
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57292-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- CDCA7L (Cell Division Cycle Associated 7-Like (CDCA7L))
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Andere Bezeichnung
- CDCA7L
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Hintergrund
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Background Information: CDCA7L plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter.CDCA7L plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. CDCA7L is involved in apoptotic signaling pathways. CDCA7L may act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
Gene Name: Cell division cycle associated 7-like
Alternative Symbols: R1, JPO2, RAM2
Protein Name: Cell division cycle-associated 7-like protein
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Molekulargewicht
- 46kDa
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Gen-ID
- 55536
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NCBI Accession
- NP_001120842
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UniProt
- B3KTR5
Target
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