CDCA7L Antikörper (C-Term)

Produktnummer ABIN1881189

Produktdetails anti-CDCA7L Antikörper

Target: CDCA7L (Cell Division Cycle Associated 7-Like (CDCA7L))

Bindungsspezifität: AA 290-317, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDCA7L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CDCA7L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-317 amino acids from the C-terminal region of human CDCA7L.

Klon: RB43388

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-CDCA7L Antikörper (ABIN1881189)

Huang, Ho, Ponzielli, Barsyte-Lovejoy, Bouffet, Picard, Hawkins, Penn: "Identification of a novel c-Myc protein interactor, JPO2, with transforming activity in medulloblastoma cells." in: Cancer research, Vol. 65, Issue 13, pp. 5607-19, (2005) (PubMed).

Chen, Ou, Chen, Choi, Shih: "R1, a novel repressor of the human monoamine oxidase A." in: The Journal of biological chemistry, Vol. 280, Issue 12, pp. 11552-9, (2005) (PubMed).

Scherer, Cheung, MacDonald, Osborne, Nakabayashi, Herbrick, Carson, Parker-Katiraee, Skaug, Khaja, Zhang, Hudek, Li, Haddad, Duggan, Fernandez, Kanematsu, Gentles, Christopoulos, Choufani, Kwasnicka et al.: "Human chromosome 7: DNA sequence and biology. ..." in: Science (New York, N.Y.), Vol. 300, Issue 5620, pp. 767-72, (2003) (PubMed).

Details zu CDCA7L

Target: CDCA7L (Cell Division Cycle Associated 7-Like (CDCA7L))

Andere Bezeichnung: CDCA7L (CDCA7L Produkte)

Synonyme: ram2 antikoerper, MGC154777 antikoerper, BC006933 antikoerper, JPO2 antikoerper, R1 antikoerper, RAM2 antikoerper, RAPGEF5 antikoerper, cell division cycle associated 7 like antikoerper, cell division cycle associated 7 like L homeolog antikoerper, cell division cycle-associated 7-like protein antikoerper, CDCA7L antikoerper, cdca7l.L antikoerper, LOC100454683 antikoerper, Cdca7l antikoerper

Hintergrund: Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways, May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.

UniProt: B3KTR5