PIDD Antikörper (N-Term)

Produktnummer ABIN2787143

Dieses Anti-PIDD-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PIDD in WB. Geeignet für Human, Ratte und Maus.

Kurzübersicht für PIDD Antikörper (N-Term) (ABIN2787143)

Target: PIDD (P53-Induced Death Domain Protein (PIDD))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIDD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PIDD Antikörper

Bindungsspezifität: N-Term

Sequenz: RLQGNPLGEA SPDAPSSPVA ALIPEMPRLF LTSDLDSFPV TPQGCSVTLA

Homologie: Human: 100%, Mouse: 86%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against LRDD. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LRDD

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 753 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PIDD

Target: PIDD (P53-Induced Death Domain Protein (PIDD))

Andere Bezeichnung: LRDD

Hintergrund: The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-c
Alias Symbols: DKFZp434D229, MGC16925, PIDD, LRDD
Protein Interaction Partner: CRADD, CRYAB, MDFI, SOX8, KEAP1, TEAD3, MAFG, AFP, RPAP3, FANCI, SENP3, TRIM32, ANP32B, HAX1, TELO2, NUP93, AIFM1, RFC5, RFC4, PRKDC, PPP6C, POLR2B, POLD1, PCNA, PRDX1, MCM7, ERCC5, ERCC2, DDB1, CASP2, FADD, RIPK1, IKBKG, CCDC85B, EFEMP2, MADD,
Protein Size: 753

Molekulargewicht: 83 kDa

Gen-ID: 55367

NCBI Accession: NM_018494, NP_060964

Pathways: p53 Signalweg, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity