PINX1 Antikörper (Middle Region)
Kurzübersicht für PINX1 Antikörper (Middle Region) (ABIN2787041)
Target
Alle PINX1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Verwendungszweck
- PINX1 Antibody - middle region
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Sequenz
- EKKSFSLEEK SKISKNRVHY MKFTKGKDLS SRSKTDLDCI FGKRQSKKTP
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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Produktmerkmale
- This is a rabbit polyclonal antibody against PINX1. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PINX1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57058-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))
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Andere Bezeichnung
- PINX1
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Hintergrund
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Background Information: PINX1 is a microtubule-binding protein essential for faithful chromosome segregation. PINX1 mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. PINX1 inhibits telomerase activity and may inhibit cell proliferation and act as tumor suppressor.
Gene Name: PIN2/TERF1 interacting, telomerase inhibitor 1
Alternative Symbols: Gno1, LPTL, LPTS, Pxr1
Protein Name: PIN2/TERF1-interacting telomerase inhibitor 1
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Molekulargewicht
- 37kDa
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Gen-ID
- 54984
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NCBI Accession
- NP_060354
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UniProt
- Q96BK5
Target
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