Relaxin 1 Antikörper (Middle Region)

Produktnummer ABIN2786863

Der Kaninchen Polyklonal Anti-Relaxin 1-Antikörper wurde für WB validiert. Er ist geeignet, Relaxin 1 in Proben von Human, Ratte und Schwein zu detektieren.

Kurzübersicht für Relaxin 1 Antikörper (Middle Region) (ABIN2786863)

Target: Relaxin 1 (RLN1)

Reaktivität: Human, Ratte, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Relaxin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Relaxin 1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: EIVPSFINKD TETIIIMLEF IANLPPELKA ALSERQPSLP ELQQYVPALK

Homologie: Human: 100%, Pig: 92%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against RLN1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RLN1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 185 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Relaxin 1

Target: Relaxin 1 (RLN1)

Andere Bezeichnung: RLN1

Hintergrund: Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. This encoded protein is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds, however, their exact cleavage sites have not been described. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. This gene has multiple polyadenylation sites. There are multiple alternatively spliced transcript variants described for this gene but their full length nature is not known yet.
Alias Symbols: H1, RLXH1, bA12D24.3.1, bA12D24.3.2
Protein Interaction Partner: RXFP1,
Protein Size: 185

Molekulargewicht: 21 kDa

Gen-ID: 6013

NCBI Accession: NM_006911, NP_008842

UniProt: P04808