PDE4D Antikörper (C-Term)

Produktnummer ABIN2786831

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PDE4D in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Kaninchen, Meerschweinchen und Zebrafisch (Danio rerio).

Kurzübersicht für PDE4D Antikörper (C-Term) (ABIN2786831)

Target: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE4D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PDE4D Antikörper

Bindungsspezifität: C-Term

Sequenz: FQFELTLEED GESDTEKDSG SQVEEDTSCS DSKTLCTQDS ESTEIPLDEQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PDE4D. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PDE4D

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PDE4D

Target: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Andere Bezeichnung: PDE4D

Hintergrund: This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.
Protein Interaction Partner: MAGEA6, GOLGA8F, GOLGA8EP, COIL, TRAF1, ZBTB1, HDGFRP2, BIN1, MAPK1, PIAS4, PRKACA, UBC, SRC, SPTBN1, PIK3CA, LYN, GRB2, FYN, ARRB2, ARRB1, ABL1, APP, PAFAH1B1, CDK2, PPP3R1, PPP3CB, PPP3CA, GSK3B, CSNK1A1, ITSN1, SUMO2, GNB2L1, MDM2, Bub1, PDE4DIP, AKAP6
Protein Size: 507

Molekulargewicht: 55 kDa

Gen-ID: 5144

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling