PDE4D Antikörper (C-Term)

Produktnummer ABIN2786831

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PDE4D in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Kaninchen, Meerschweinchen und Zebrafisch (Danio rerio).

Kurzübersicht für PDE4D Antikörper (C-Term) (ABIN2786831)

Target: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE4D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PDE4D Antikörper

Bindungsspezifität: C-Term

Sequenz: FQFELTLEED GESDTEKDSG SQVEEDTSCS DSKTLCTQDS ESTEIPLDEQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PDE4D. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PDE4D

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PDE4D

Target: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Andere Bezeichnung: PDE4D

Hintergrund: This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.
Protein Interaction Partner: MAGEA6, GOLGA8F, GOLGA8EP, COIL, TRAF1, ZBTB1, HDGFRP2, BIN1, MAPK1, PIAS4, PRKACA, UBC, SRC, SPTBN1, PIK3CA, LYN, GRB2, FYN, ARRB2, ARRB1, ABL1, APP, PAFAH1B1, CDK2, PPP3R1, PPP3CB, PPP3CA, GSK3B, CSNK1A1, ITSN1, SUMO2, GNB2L1, MDM2, Bub1, PDE4DIP, AKAP6
Protein Size: 507

Molekulargewicht: 55 kDa

Gen-ID: 5144

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling