SFRP2 Antikörper (Middle Region)

Produktnummer ABIN2786763

Der Kaninchen Polyklonal Anti-SFRP2-Antikörper wurde für WB validiert. Er ist geeignet, SFRP2 in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Schwein, Kaninchen, Schaf und Meerschweinchen zu detektieren.

Kurzübersicht für SFRP2 Antikörper (Middle Region) (ABIN2786763)

Target: SFRP2 (Secreted Frizzled-Related Protein 2 (SFRP2))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Schwein, Kaninchen, Schaf, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SFRP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SFRP2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: DRFPQDNDLC IPLASSDHLL PATEEAPKVC EACKNKNDDD NDIMETLCKN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SFRP2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SFRP2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 295 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SFRP2

Target: SFRP2 (Secreted Frizzled-Related Protein 2 (SFRP2))

Andere Bezeichnung: SFRP2

Hintergrund: SFRP2 is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer.This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FRP-2, SARP1, SDF-5
Protein Interaction Partner: WNT4, PAX2, WNT1, FN1,
Protein Size: 295

Molekulargewicht: 31 kDa

Gen-ID: 6423

NCBI Accession: NM_003013, NP_003004

UniProt: Q96HF1

Pathways: WNT Signalweg, Tube Formation, Positive Regulation of Endopeptidase Activity, Negative Regulation of intrinsic apoptotic Signaling, Positive Regulation of fat Cell Differentiation