SET/TAF-I Antikörper (N-Term)

Produktnummer ABIN2786762

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SET/TAF-I in WB, IHC und IP. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Pferd, Meerschweinchen, Kaninchen und Hund.Es wurde in 1 Publikation zitiert.

Kurzübersicht für SET/TAF-I Antikörper (N-Term) (ABIN2786762)

Target: SET/TAF-I (SET) (SET Nuclear Oncogene (SET))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Pferd, Meerschweinchen, Kaninchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SET/TAF-I Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Produktdetails anti-SET/TAF-I Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: SET Antibody - N-terminal region

Sequenz: IDEVQNEIDR LNEQASEEIL KVEQKYNKLR QPFFQKRSEL IAKIPNFWVT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SET. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SET

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56542-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SET/TAF-I Antikörper (ABIN2786762)

Pronobis, Zheng, Singh, Goldman, Poss: "In vivo proximity labeling identifies cardiomyocyte protein networks during zebrafish heart regeneration." in: eLife, Vol. 10, (2021) (PubMed).

Details zu SET/TAF-I

Target: SET/TAF-I (SET) (SET Nuclear Oncogene (SET))

Andere Bezeichnung: SET

Hintergrund:

Background Information: SET is a multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone binding. Isoform 2 anti-apoptotic activity is mediated by inhibition of the GZMA-activated DNase, NME1. In the course of cytotoxic T-lymphocyte (CTL)-indu

Gene Name: SET nuclear oncogene

Alternative Symbols: 2PP2A, IGAAD, MRD58, TAF-I, I2PP2A, IPP2A2, PHAPII, TAF-IBETA

Protein Name: cDNA, FLJ96345, Homo sapiens SET translocation (myeloid leukemia-associated) (SET),mRNA EMBL BAG37717.1

Molekulargewicht: 32kDa

Gen-ID: 6418

NCBI Accession: NP_003002

UniProt: B2RCX0

Pathways: Apoptose