SCP2 Antikörper (Middle Region)

Produktnummer ABIN2786761

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SCP2 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Meerschweinchen, Pferd und Zebrafisch (Danio rerio).

Kurzübersicht für SCP2 Antikörper (Middle Region) (ABIN2786761)

Target: SCP2 (Sterol Carrier Protein 2 (SCP2))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SCP2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: NHKHSVNNPY SQFQDEYSLD EVMASKEVFD FLTILQCCPT SDGAAAAILA

Homologie: Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SCP2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SCP2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 322 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SCP2

Target: SCP2 (Sterol Carrier Protein 2 (SCP2))

Andere Bezeichnung: SCP2

Hintergrund: SCP2 protein is thought to be an intracellular lipid transfer protein. SCP2 is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis.This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. The full-length nature of all transcript variants has not been determined.
Alias Symbols: DKFZp686C12188, DKFZp686D11188, NLTP, NSL-TP, SCPX, SCP-2, SCP-X, SCP-CHI
Protein Interaction Partner: TRIP13, UBC, PEX5, MPLKIP, MRRF, SUGP1, MRPS28, TBL2, SRRM2, RAB31, SEPT9, TIMM44, ECI2, SCO2, AGPS, STX7, UBL4A, VDAC3, VDAC2, RRBP1, RBMS1, NDUFA7, IDH3G, HSD17B4, ACAA1, RAB8A, ELAVL1, CACNA1A, ACAA2, EHHADH, CAV1, ACOX1, PITPNA,
Protein Size: 322

Molekulargewicht: 35 kDa

Gen-ID: 6342

NCBI Accession: NM_001007098, NP_001007099

UniProt: Q6NXF4

Pathways: C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process