RPA1 Antikörper (Middle Region)
Kurzübersicht für RPA1 Antikörper (Middle Region) (ABIN2786755)
Target
Alle RPA1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- SRGEGKLFSL ELVDESGEIR ATAFNEQVDK FFPLIEVNKV YYFSKGTLKI
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 93%, Zebrafish: 92%
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Produktmerkmale
- This is a rabbit polyclonal antibody against RPA1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human RPA1
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 616 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RPA1 (Replication Protein A1, 70kDa (RPA1))
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Andere Bezeichnung
- RPA1
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Hintergrund
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RPA1 plays an essential role in several cellular processes in DNA metabolism including replication, recombination and DNA repair. RPA1 binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing
Alias Symbols: HSSB, REPA1, RF-A, RP-A, RPA70, MST075
Protein Interaction Partner: STRA13, UBC, MTUS2, APITD1, PCNA, SUMO2, FBXO18, ATRX, MAP4, CAPRIN1, LMO7, LIG3, LDHA, ITGB1, IMPDH2, ILF3, ILF2, HSPB1, HSPA8, HSPA5, HNRNPU, HNRNPL, HNRNPK, HNRNPH1, HNRNPF, HNRNPD, HNRNPAB, HNRNPA2B1, HNRNPA1, HCFC1, GTF3C2, GTF2I, GTF2H3, GAPDH, XRCC
Protein Size: 616 -
Molekulargewicht
- 68 kDa
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Gen-ID
- 6117
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NCBI Accession
- NM_002945, NP_002936
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UniProt
- P27694
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Pathways
- Telomere Maintenance, DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
Target
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