PIM1 Antikörper (N-Term)
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- Target Alle PIM1 Antikörper anzeigen
- PIM1 (Pim-1 Oncogene (PIM1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Pferd, Schaf, Rind (Kuh), Hund, Kaninchen, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PIM1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- MLLSKINSLA HLRAAPCNDL HATKLAPGKE KEPLESQYQV GPLLGSGGFG
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PIM1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PIM1
- Top Product
- Discover our top product PIM1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 313 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PIM1 (Pim-1 Oncogene (PIM1))
- Andere Bezeichnung
- PIM1 (PIM1 Produkte)
- Hintergrund
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PIM1 may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3. Isoform 2 promotes the G1/S transition of the cell cycle via up-regulation of CDK2 activity and phosphorylation of CDKN1B, resulting in enhanced nuclear export and
Alias Symbols: PIM
Protein Interaction Partner: FXR2, NHLH1, FH, BEND7, HEXIM2, BANP, TFPT, ZBTB1, UBC, APP, MARK3, HSP90AA1, HSPA4, PIM1, MDM2, ELAVL1, FZR1, SKP2, PPP2R5E, PPP2R4, PPP2CA, PIN1, CDC34, CDC20, ABCB1, HIST2H3C, MYC, MAX, SNX6, CBX1, CBX3, BAD, HIST3H3, SND1, PTPRO, NFATC1, SHMT1, EPHA3,
Protein Size: 404 - Molekulargewicht
- 45 kDa
- Gen-ID
- 5292
- NCBI Accession
- NM_002648, NP_002639
- Pathways
- Glycosaminoglycan Metabolic Process
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