SERPINB2 Antikörper (Middle Region)

Produktnummer ABIN2786668

Produktdetails anti-SERPINB2 Antikörper

Target: SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Hund, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SERPINB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GKIPNLLPEG SVDGDTRMVL VNAVYFKGKW KTPFEKKLNG LYPFRVNSAQ

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 85%, Sheep: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against SERPINB2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SERPINB2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 415 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SERPINB2 Antikörper (ABIN2786668)

Stutchbury, Al-Ejeh, Stillfried, Croucher, Andrews, Irving, Links, Ranson: "Preclinical evaluation of 213Bi-labeled plasminogen activator inhibitor type 2 in an orthotopic murine xenogenic model of human breast carcinoma." in: Molecular cancer therapeutics, Vol. 6, Issue 1, pp. 203-12, (2007) (PubMed).

Details zu SERPINB2

Target: SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))

Andere Bezeichnung: SERPINB2 (SERPINB2 Produkte)

Synonyme: HsT1201 antikoerper, PAI antikoerper, PAI-2 antikoerper, PAI2 antikoerper, PLANH2 antikoerper, SERPINB2 antikoerper, Planh2 antikoerper, ovalbumin antikoerper, Pai2a antikoerper, serpin family B member 2 antikoerper, serpin peptidase inhibitor, clade B (ovalbumin), member 2 antikoerper, serine (or cysteine) peptidase inhibitor, clade B, member 2 antikoerper, SERPINB2 antikoerper, Serpinb2 antikoerper

Substanzklasse: Amino Acid

Hintergrund: SERPINB2 inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.
Alias Symbols: HsT1201, PAI, PAI-2, PAI2, PLANH2
Protein Interaction Partner: UBC, APP, PRPF8, PSMB1, RBL2, RB1, IRF3, PLAU, SERPINB2,
Protein Size: 415

Molekulargewicht: 44 kDa

Gen-ID: 5055

NCBI Accession: NM_002575, NP_002566

UniProt: P05120

Pathways: Autophagie