Sec8 Antikörper (N-Term)

Produktnummer ABIN2786600

Der Kaninchen Polyklonal Anti-Sec8-Antikörper wurde für WB validiert. Er ist geeignet, Sec8 in Proben von Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Kaninchen, Hund und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für Sec8 Antikörper (N-Term) (ABIN2786600)

Target: Sec8 (EXOC4) (Exocyst Complex Component 4 (EXOC4))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Kaninchen, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Sec8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Sec8 Antikörper

Bindungsspezifität: N-Term

Sequenz: MAAEAAGGKY RSTVSKSKDP SGLLISVIRT LSTSDDVEDR ENEKGRLEEA

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against EXOC4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EXOC4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 473 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Sec8

Target: Sec8 (EXOC4) (Exocyst Complex Component 4 (EXOC4))

Andere Bezeichnung: EXOC4

Hintergrund: The specific function of this protein remains unknown.The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: MGC27170, REC8, SEC8, SEC8L1, Sec8p
Protein Interaction Partner: SUMO2, UBC, EXOC2, EXOC7, ATG5, ATG12, BECN1, EXOC8, EGFR, EXOC1, EXOC3, nef, IQCB1, EXOC5, UBD, MYO5A, DTNBP1, CEP63, DISC1, Poc1b, GTF2E2, DLGAP4, DLG3, RALA, GRIN2B, DLG4, MYC,
Protein Size: 473

Molekulargewicht: 54 kDa

Gen-ID: 60412

NCBI Accession: NM_001037126, NP_001032203

UniProt: Q8TAR2

Pathways: Peptide Hormone Metabolism, Synaptic Vesicle Exocytosis