PAIP2 Antikörper (N-Term)

Produktnummer ABIN2786594

Produktdetails anti-PAIP2 Antikörper

Target: PAIP2 (Poly Binding Protein Interacting Protein 2 (PAIP2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Schwein, Kaninchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAIP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MKDPSRSSTS PSIINEDVII NGHSHEDDNP FAEYMWMENE EEFNRQIEEE

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PAIP2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 127 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PAIP2

Target: PAIP2 (Poly Binding Protein Interacting Protein 2 (PAIP2))

Andere Bezeichnung: PAIP2 (PAIP2 Produkte)

Synonyme: PAIP2A antikoerper, DKFZp469O1314 antikoerper, 2310050K10Rik antikoerper, AU045972 antikoerper, paip2 antikoerper, poly(A) binding protein interacting protein 2 antikoerper, polyadenylate-binding protein-interacting protein 2 antikoerper, poly(A) binding protein interacting protein 2B L homeolog antikoerper, PAIP2 antikoerper, Paip2 antikoerper, paip2b.L antikoerper

Hintergrund: PAIP2 acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. It displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
Alias Symbols: MGC72018, PAIP2A
Protein Interaction Partner: PABPC1, BAG3, RPL11, IGBP1, APP, UBC, UBR5, ELAVL1,
Protein Size: 127

Molekulargewicht: 14 kDa

Gen-ID: 51247

NCBI Accession: NM_016480, NP_057564

UniProt: Q9BPZ3