PAIP2 Antikörper (N-Term)
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- Target Alle PAIP2 Antikörper anzeigen
- PAIP2 (Poly Binding Protein Interacting Protein 2 (PAIP2))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PAIP2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- MKDPSRSSTS PSIINEDVII NGHSHEDDNP FAEYMWMENE EEFNRQIEEE
- Homologie
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PAIP2. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product PAIP2 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 127 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PAIP2 (Poly Binding Protein Interacting Protein 2 (PAIP2))
- Andere Bezeichnung
- PAIP2 (PAIP2 Produkte)
- Hintergrund
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PAIP2 acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. It displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
Alias Symbols: MGC72018, PAIP2A
Protein Interaction Partner: PABPC1, BAG3, RPL11, IGBP1, APP, UBC, UBR5, ELAVL1,
Protein Size: 127 - Molekulargewicht
- 14 kDa
- Gen-ID
- 51247
- NCBI Accession
- NM_016480, NP_057564
- UniProt
- Q9BPZ3
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