RPL5 Antikörper (N-Term)

Produktnummer ABIN2786525

Produktdetails anti-RPL5 Antikörper

Target: RPL5 (Ribosomal Protein L5 (RPL5))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPL5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RLVIQDKNKY NTPKYRMIVR VTNRDIICQI AYARIEGDMI VCAAYAHELP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RPL5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RPL5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 297 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RPL5

Target: RPL5 (Ribosomal Protein L5 (RPL5))

Andere Bezeichnung: RPL5 (RPL5 Produkte)

Synonyme: DBA6 antikoerper, L5 antikoerper, U21RNA antikoerper, CG17489 antikoerper, Dmel\\CG17489 antikoerper, E-2d antikoerper, M(2)40B antikoerper, Rp L5 antikoerper, Rpl5 antikoerper, dRPL5 antikoerper, yip6 antikoerper, rpl5 antikoerper, wu:fj02g05 antikoerper, zgc:86854 antikoerper, mg:cb01f08 antikoerper, rpl5l antikoerper, zgc:56511 antikoerper, zgc:77176 antikoerper, ribosomal protein L5 antikoerper, 60S ribosomal protein L5 antikoerper, Ribosomal protein L5 antikoerper, ribosomal protein L5 L homeolog antikoerper, 50S ribosomal protein L5 antikoerper, ribosomal protein L5 S homeolog antikoerper, ribosomal protein L5b antikoerper, rpl5 antikoerper, ribosomal protein L5a antikoerper, Rpl5 antikoerper, RPL5 antikoerper, rpl-5 antikoerper, RpL5 antikoerper, rpl5.L antikoerper, rpl5 antikoerper, rpl5.S antikoerper, rpl5b antikoerper, rpl5a antikoerper

Hintergrund: RPL5 is required for rRNA maturation and formation of the 60S ribosomal subunits. This protein binds 5S RNA.Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L18P family of ribosomal proteins. It is located in the cytoplasm. The protein binds 5S rRNA to form a stable complex called the 5S ribonucleoprotein particle (RNP), which is necessary for the transport of nonribosome-associated cytoplasmic 5S rRNA to the nucleolus for assembly into ribosomes. The protein interacts specifically with the beta subunit of casein kinase II. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. This gene is co-transcribed with the small nucleolar RNA gene U21, which is located in its fifth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC117339, MSTP030, L5, DBA6
Protein Interaction Partner: HUWE1, UBC, PML, HAUS2, CEP250, TUBG1, TP53, SUMO2, SUMO3, STAU1, LGR4, VHL, RPL5, FBXO6, UPF2, TARDBP, IGSF8, ICAM1, CD81, PAN2, UBL4A, NOS2, VCAM1, MDM2, ITGA4, HSP90AB1, HSP90AA1, FN1, CSNK2A1, RPS3, RPL11, NPM1, ESR1, CBX5, EEF2, EEF1G, EEF1A1, DHX9,
Protein Size: 297

Molekulargewicht: 34 kDa

Gen-ID: 6125

NCBI Accession: NM_000969, NP_000960

UniProt: P46777