RPL5 Antikörper (C-Term)

Produktnummer ABIN6257834

Produktdetails anti-RPL5 Antikörper

Target: RPL5 (Ribosomal Protein L5 (RPL5))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPL5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: RPL5 Antibody detects endogenous levels of total RPL5.

Homologie: Bovine,Horse,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RPL5, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu RPL5

Target: RPL5 (Ribosomal Protein L5 (RPL5))

Andere Bezeichnung: RPL5 (RPL5 Produkte)

Synonyme: DBA6 antikoerper, L5 antikoerper, U21RNA antikoerper, CG17489 antikoerper, Dmel\\CG17489 antikoerper, E-2d antikoerper, M(2)40B antikoerper, Rp L5 antikoerper, Rpl5 antikoerper, dRPL5 antikoerper, yip6 antikoerper, rpl5 antikoerper, wu:fj02g05 antikoerper, zgc:86854 antikoerper, mg:cb01f08 antikoerper, rpl5l antikoerper, zgc:56511 antikoerper, zgc:77176 antikoerper, ribosomal protein L5 antikoerper, 60S ribosomal protein L5 antikoerper, Ribosomal protein L5 antikoerper, ribosomal protein L5 L homeolog antikoerper, 50S ribosomal protein L5 antikoerper, ribosomal protein L5 S homeolog antikoerper, ribosomal protein L5b antikoerper, rpl5 antikoerper, ribosomal protein L5a antikoerper, Rpl5 antikoerper, RPL5 antikoerper, rpl-5 antikoerper, RpL5 antikoerper, rpl5.L antikoerper, rpl5 antikoerper, rpl5.S antikoerper, rpl5b antikoerper, rpl5a antikoerper

Hintergrund:

Description: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. As part of the 5S RNP/5S ribonucleoprotein particle it is an essential component of the LSU, required for its formation and the maturation of rRNAs (PubMed:12962325, PubMed:19061985, PubMed:24120868, PubMed:23636399). It also couples ribosome biogenesis to p53/TP53 activation. As part of the 5S RNP it accumulates in the nucleoplasm and inhibits MDM2, when ribosome biogenesis is perturbed, mediating the stabilization and the activation of TP53 (PubMed:24120868).

Gene: RPL5

Molekulargewicht: 34 kDa

Gen-ID: 6125

UniProt: P46777