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IL-15 Antikörper (N-Term)

IL15 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Schaf, Meerschweinchen, Schwein, Pferd, Hund WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2786287
  • Target Alle IL-15 (IL15) Antikörper anzeigen
    IL-15 (IL15) (Interleukin 15 (IL15))
    Bindungsspezifität
    • 38
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 61
    • 22
    • 9
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Kaninchen, Schaf, Meerschweinchen, Schwein, Pferd, Hund
    Wirt
    • 68
    • 25
    • 4
    • 3
    • 3
    • 1
    Kaninchen
    Klonalität
    • 77
    • 27
    Polyklonal
    Konjugat
    • 63
    • 20
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL-15 Antikörper ist unkonjugiert
    Applikation
    • 71
    • 38
    • 35
    • 19
    • 18
    • 12
    • 10
    • 9
    • 9
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    RISKPHLRSI SIQCYLCLLL NSHFLTEAGI HVFILGCFSA GLPKTEANWV
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against IL15. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human IL15
    Top Product
    Discover our top product IL15 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 162 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    IL-15 (IL15) (Interleukin 15 (IL15))
    Andere Bezeichnung
    IL15 (IL15 Produkte)
    Synonyme
    IL15 antikoerper, AI503618 antikoerper, IL-15 antikoerper, interleukin 15 antikoerper, IL15 antikoerper, Il15 antikoerper
    Hintergrund
    IL15 is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.
    Alias Symbols: IL-15, MGC9721
    Protein Interaction Partner: ZNRD1, TRAF3, STAT5B, APP, IL15RA, IL2RG, IL2RB,
    Protein Size: 162
    Molekulargewicht
    13 kDa
    Gen-ID
    3600
    NCBI Accession
    NM_172174, NP_751914
    UniProt
    P40933
    Pathways
    JAK-STAT Signalweg, Glycosaminoglycan Metabolic Process
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