Epsin 2 Antikörper (Middle Region)

Produktnummer ABIN503706

Produktdetails anti-Epsin 2 Antikörper

Target: Epsin 2 (EPN2)

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Epsin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: DPFESQPLTV ASSKPSSARK TPESFLGPNA ALVNLDSLVT RPAPPAQSLN

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against EPN2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EPN2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 584 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Epsin 2

Target: Epsin 2 (EPN2)

Andere Bezeichnung: EPN2 (EPN2 Produkte)

Hintergrund: EPN2 is a protein which interacts with clathrin and adaptor-related protein complex 2, alpha 1 subunit. The protein is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery. The protein is thought to be involved in clathrin-mediated endocytosis.This gene encodes a protein which interacts with clathrin and adaptor-related protein complex 2, alpha 1 subunit. The protein is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery. The protein is thought to be involved in clathrin-mediated endocytosis. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
Alias Symbols: EHB21, KIAA1065
Protein Interaction Partner: rev, UBC, APOE, UBQLN2, ITSN1, RNF11, EPS15, YWHAG, TUBA1B, LAPTM5, CLTC, TFAP2A, Eps15l1,
Protein Size: 584

Molekulargewicht: 62 kDa

Gen-ID: 22905

NCBI Accession: NM_148921, NP_683723

UniProt: Q52LD0

Pathways: EGFR Downregulation