CCDC11 Antikörper (N-Term)

Produktnummer ABIN2786216

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CCDC11 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Meerschweinchen, Pferd, Schwein, Rind (Kuh) und Hund. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für CCDC11 Antikörper (N-Term) (ABIN2786216)

Target: CCDC11 (Coiled-Coil Domain Containing 11 (CCDC11))

Reaktivität: Human, Meerschweinchen, Pferd, Schwein, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCDC11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CCDC11 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: CFAP53 Antibody - N-terminal region

Sequenz: YSQRFGTVQR EVKGPTPKVV IVRSKPPKGQ GAEHHLERIR RSHQKHNAIL

Homologie: Cow: 93%, Dog: 79%, Guinea Pig: 77%, Horse: 85%, Human: 100%, Pig: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against CCDC11. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CCDC11

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55454-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CCDC11 Antikörper (ABIN2786216)

Perles, Cinnamon, Ta-Shma, Shaag, Einbinder, Rein, Elpeleg: "A human laterality disorder associated with recessive CCDC11 mutation." in: Journal of medical genetics, Vol. 49, Issue 6, pp. 386-90, (2012) (PubMed).

Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).

Details zu CCDC11

Target: CCDC11 (Coiled-Coil Domain Containing 11 (CCDC11))

Andere Bezeichnung: CFAP53

Hintergrund:

Background Information: This gene belongs to the CFAP53 family. It was found to be differentially expressed by the ciliated cells of frog epidermis and in skin fibroblasts from human. Mutations in this gene are associated with visceral heterotaxy-6, which implicates this gene in determination of left-right asymmetric patterning.

Gene Name: cilia and flagella associated protein 53

Alternative Symbols: HTX6, CCDC11

Protein Name: cilia- and flagella-associated protein 53

Molekulargewicht: 62kDa

Gen-ID: 220136

NCBI Accession: NP_659457

UniProt: Q96M91