FANCE Antikörper (Middle Region)

Produktnummer ABIN2786176

Der Kaninchen Polyklonal anti-FANCE Antikörper (ABIN2786176) detektiert spezifisch FANCE in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Rind (Kuh), Pferd, Schwein, Kaninchen und Hund.

Kurzübersicht für FANCE Antikörper (Middle Region) (ABIN2786176)

Target: FANCE (Fanconi Anemia, Complementation Group E (FANCE))

Reaktivität: Human, Rind (Kuh), Pferd, Schwein, Kaninchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FANCE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FANCE Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: FANCE Antibody - middle region

Sequenz: SPQAPDPEEE ENRDSQQPGK RRKDSEEEAA SPEGKRVPKR LRCWEEEEDH

Homologie: Cow: 86%, Dog: 79%, Horse: 85%, Human: 100%, Pig: 79%, Rabbit: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against FANCE. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FANCE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55381-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu FANCE

Target: FANCE (Fanconi Anemia, Complementation Group E (FANCE))

Andere Bezeichnung: FANCE

Hintergrund:

Background Information: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex.The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group E. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Fanconi anemia, complementation group E

Alternative Symbols: FAE, FACE

Protein Name: Fanconi anemia group E protein

Molekulargewicht: 59kDa

Gen-ID: 2178

NCBI Accession: NP_068741

UniProt: Q9HB96

Pathways: DNA Reparatur