FANCE Antikörper (Middle Region)

Produktnummer ABIN2786176

Dieses Anti-FANCE-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FANCE in WB. Geeignet für Human, Rind (Kuh), Pferd, Schwein, Kaninchen und Hund.

Kurzübersicht für FANCE Antikörper (Middle Region) (ABIN2786176)

Target: FANCE (Fanconi Anemia, Complementation Group E (FANCE))

Reaktivität: Human, Rind (Kuh), Pferd, Schwein, Kaninchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FANCE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FANCE Antikörper

Bindungsspezifität: Middle Region

Sequenz: SPQAPDPEEE ENRDSQQPGK RRKDSEEEAA SPEGKRVPKR LRCWEEEEDH

Homologie: Cow: 86%, Dog: 79%, Horse: 85%, Human: 100%, Pig: 79%, Rabbit: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against FANCE. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FANCE

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 536 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FANCE

Target: FANCE (Fanconi Anemia, Complementation Group E (FANCE))

Andere Bezeichnung: FANCE

Hintergrund: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex.The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group E. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FACE, FAE
Protein Interaction Partner: APITD1, STRA13, UBC, FANCG, FANCD2, FANCC, FANCA, FANCM, C1orf86, ELAVL1, Erh, FANCF, CHEK1, HES1, PCNA, BRCA2,
Protein Size: 536

Molekulargewicht: 59 kDa

Gen-ID: 2178

NCBI Accession: NM_021922, NP_068741

UniProt: Q9HB96

Pathways: DNA Reparatur