KIFAP3 Antikörper (Middle Region)

Produktnummer ABIN2786068

Der Kaninchen Polyklonal anti-KIFAP3 Antikörper wird verwendet zum Nachweis von KIFAP3 in Proben von Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Hund. Er wurde validiert für WB.

Kurzübersicht für KIFAP3 Antikörper (Middle Region) (ABIN2786068)

Target: KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIFAP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KIFAP3 Antikörper

Bindungsspezifität: Middle Region

Sequenz: WLEMVESRQM DESEQYLYGD DRIEPYIHEG DILERPDLFY NSDGLIASEG

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against KIFAP3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KIFAP3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 792 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu KIFAP3

Target: KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))

Andere Bezeichnung: KIFAP3

Hintergrund: The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras, one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein.
Alias Symbols: FLJ22818, KAP3, SMAP, Smg-GDS, dJ190I16.1, KAP-3
Protein Interaction Partner: NAA10, NCF2, UBC, PEX19, RBFOX1, KIF3A, VHL, RANBP2, MEST, DISC1, NIPSNAP3A, NUDT21, AR, RAP1GDS1, MINK1, SMC3, KIF3B, KIFAP3, MAP3K10, RPGR, SRC, APC, MAP3K11,
Protein Size: 792

Molekulargewicht: 91 kDa

Gen-ID: 22920

NCBI Accession: NM_014970, NP_055785

UniProt: Q92845

Pathways: Hedgehog Signalweg, Sensory Perception of Sound