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OPTC Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-OPTC-Antikörper wurde für WB validiert. Er ist geeignet, OPTC in Proben von Human, Maus, Ratte, Schwein, Hund, Meerschweinchen, Rind (Kuh), Pferd, Kaninchen und Zebrafisch (Danio rerio) zu detektieren.
Produktnummer ABIN2786017

Kurzübersicht für OPTC Antikörper (C-Term) (ABIN2786017)

Target

Alle OPTC Antikörper anzeigen
OPTC (Opticin (OPTC))

Reaktivität

Human, Maus, Ratte, Schwein, Hund, Meerschweinchen, Rind (Kuh), Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt

  • 19
  • 1
  • 1
Kaninchen

Klonalität

  • 19
  • 2
Polyklonal

Konjugat

  • 13
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Dieser OPTC Antikörper ist unkonjugiert

Applikation

  • 11
  • 8
  • 6
  • 6
  • 4
  • 4
  • 2
  • 2
  • 2
Western Blotting (WB)
  • Bindungsspezifität

    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term

    Sequenz

    LSDNLLDSIP GPLPLSLRSV HLQNNLIETM QRDVFCDPEE HKHTRRQLED

    Homologie

    Cow: 77%, Dog: 100%, Guinea Pig: 85%, Horse: 92%, Human: 100%, Mouse: 85%, Pig: 100%, Rabbit: 92%, Rat: 100%, Zebrafish: 83%

    Produktmerkmale

    This is a rabbit polyclonal antibody against OPTC. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the C terminal region of human OPTC
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 332 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    OPTC (Opticin (OPTC))

    Andere Bezeichnung

    OPTC

    Hintergrund

    Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated with the extracellular matrix. Opticin is present in significant quantities in the vitreous of the eye and also ocalizes to the cornea, iris, ciliary body, optic nerve, choroid, retina, and fetal liver. Opticin may noncovalently bind collagen fibrils and regulate fibril morphology, spacing, and organization. The opticin gene is mapped to a region of chromosome 1 that is associated with the inherited eye diseases age-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa (AXPC1).Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated with the extracellular matrix. Opticin is present in significant quantities in the vitreous of the eye and also localizes to the cornea, iris, ciliary body, optic nerve, choroid, retina, and fetal liver. Opticin may noncovalently bind collagen fibrils and regulate fibril morphology, spacing, and organization. The opticin gene is mapped to a region of chromosome 1 that is associated with the inherited eye diseases age-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa (AXPC1).
    Alias Symbols: OPT
    Protein Interaction Partner: OSGEP, OPTC,
    Protein Size: 332

    Molekulargewicht

    35 kDa

    Gen-ID

    26254

    NCBI Accession

    NM_014359, NP_055174

    UniProt

    Q9UBM4
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