POLM Antikörper (Middle Region)
Kurzübersicht für POLM Antikörper (Middle Region) (ABIN406451)
Target
Alle POLM Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
 - Middle Region
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Sequenz
 - LRRFSRKEKG LWLNSHGLFD PEQKTFFQAA SEEDIFRHLG LEYLPPEQRN
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Homologie
 - Cow: 79%, Dog: 92%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 86%, Rat: 93%
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Produktmerkmale
 - This is a rabbit polyclonal antibody against POLM. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
 - Affinity Purified
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Immunogen
 - The immunogen is a synthetic peptide directed towards the middle region of human POLM
 
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Applikationshinweise
 - Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 494 AA
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Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Format
 - Liquid
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Konzentration
 - Lot specific
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Buffer
 - Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
 - Sodium azide
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Vorsichtsmaßnahmen
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
 - Avoid repeated freeze-thaw cycles.
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Lagerung
 - -20 °C
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Informationen zur Lagerung
 - For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
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- POLM (Polymerase (DNA Directed), mu (POLM))
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Andere Bezeichnung
 - POLM
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Hintergrund
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                        POLM seems to act as an Ig mutase which is responsible for immunoglobulin (Ig) gene hypermutation.
Alias Symbols: Tdt-N, Pol Mu
Protein Interaction Partner: CEP55, IKZF3, PNMA1, PCNA, UBE2C, UBE2H, UBE2E1, UBE2D3, UBE2D2, UBE2D1,
Protein Size: 494 - 
                                            
Molekulargewicht
 - 55 kDa
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Gen-ID
 - 27434
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NCBI Accession
 - NM_013284, NP_037416
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UniProt
 - Q9NP87
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Pathways
 - DNA Reparatur, Production of Molecular Mediator of Immune Response
 
Target
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