POLL Antikörper (Middle Region)
Kurzübersicht für POLL Antikörper (Middle Region) (ABIN2785955)
Target
Alle POLL Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- SLSEHALSTA VVRNTHGCKV GPGRVLPTPT EKDVFRLLGL PYREPAERDW
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Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%, Yeast: 83%
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Produktmerkmale
- This is a rabbit polyclonal antibody against POLL. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human POLL
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 575 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- POLL (Polymerase (DNA Directed), lambda (POLL))
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Andere Bezeichnung
- POLL
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Hintergrund
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POLL is a repair polymerase.It is involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
Alias Symbols: BETA-N, FLJ46002, POL-KAPPA, BETAN, POLKAPPA
Protein Interaction Partner: KRTAP10-3, KRTAP10-7, FAM9B, KRT40, FSD2, SSX2IP, TFIP11, PNMA1, TFCP2, MAGEA12, TRIM23, APP, DCUN1D1, REV1, LDOC1, RPA1, PCNA, CDK2, UBE2H, UBE2E1, UBE2D3, UBE2D2, UBE2D1,
Protein Size: 575 -
Molekulargewicht
- 63 kDa
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Gen-ID
- 27343
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NCBI Accession
- NM_013274, NP_037406
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UniProt
- Q9UGP5
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Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
Target
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