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POLL Antikörper (Middle Region)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch POLL in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus, Kaninchen, Rind (Kuh), Meerschweinchen, Hund und Saccharomyces cerevisiae.
Produktnummer ABIN2785955

Kurzübersicht für POLL Antikörper (Middle Region) (ABIN2785955)

Target

Alle POLL Antikörper anzeigen
POLL (Polymerase (DNA Directed), lambda (POLL))

Reaktivität

  • 24
  • 22
  • 10
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human, Ratte, Maus, Kaninchen, Rind (Kuh), Meerschweinchen, Hund, Saccharomyces cerevisiae

Wirt

  • 38
  • 1
Kaninchen

Klonalität

  • 39
Polyklonal

Konjugat

  • 21
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser POLL Antikörper ist unkonjugiert

Applikation

  • 32
  • 15
  • 13
  • 13
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 15
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Sequenz

    SLSEHALSTA VVRNTHGCKV GPGRVLPTPT EKDVFRLLGL PYREPAERDW

    Homologie

    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%, Yeast: 83%

    Produktmerkmale

    This is a rabbit polyclonal antibody against POLL. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the middle region of human POLL
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 575 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    POLL (Polymerase (DNA Directed), lambda (POLL))

    Andere Bezeichnung

    POLL

    Hintergrund

    POLL is a repair polymerase.It is involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
    Alias Symbols: BETA-N, FLJ46002, POL-KAPPA, BETAN, POLKAPPA
    Protein Interaction Partner: KRTAP10-3, KRTAP10-7, FAM9B, KRT40, FSD2, SSX2IP, TFIP11, PNMA1, TFCP2, MAGEA12, TRIM23, APP, DCUN1D1, REV1, LDOC1, RPA1, PCNA, CDK2, UBE2H, UBE2E1, UBE2D3, UBE2D2, UBE2D1,
    Protein Size: 575

    Molekulargewicht

    63 kDa

    Gen-ID

    27343

    NCBI Accession

    NM_013274, NP_037406

    UniProt

    Q9UGP5

    Pathways

    DNA Reparatur, Production of Molecular Mediator of Immune Response
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