KPNA6 Antikörper (N-Term)
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- Target Alle KPNA6 Antikörper anzeigen
- KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Schwein, Hund, Kaninchen, Pferd, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KPNA6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- STTGESVITR EMVEMLFSDD SDLQLATTQK FRKLLSKEPS PPIDEVINTP
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against KPNA6. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human KPNA6
- Top Product
- Discover our top product KPNA6 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 536 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))
- Andere Bezeichnung
- KPNA6 (KPNA6 Produkte)
- Synonyme
- IPOA7 antikoerper, Kpna5 antikoerper, NPI-2 antikoerper, KPNA7 antikoerper, karyopherin subunit alpha 6 antikoerper, karyopherin (importin) alpha 6 antikoerper, karyopherin alpha 6 (importin alpha 7) antikoerper, karyopherin alpha 6 (importin alpha 7) S homeolog antikoerper, KPNA6 antikoerper, Kpna6 antikoerper, kpna6.S antikoerper
- Hintergrund
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The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. KPNA6 is a member of the importin alpha family.Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ11249, IPOA7, KPNA7, MGC17918
Protein Interaction Partner: FRG1B, NUP50, UBC, NOP2, XRN2, rev, TTC1, PRKAR2A, LMNA, KPNA3, KPNA2, GFPT1, HDAC1, SKP2, CDKN1B, KPNB1, ZNF131, ANP32A, TAF9, CUL3, ELAVL1, KEAP1, Nipbl, Ddx21, Nhp2l1, Mki67, CREBBP, RAC1, MEPCE, RELB, CSE1L, STAT1, BRCA1, STAT3, SPOP,
Protein Size: 536 - Molekulargewicht
- 60 kDa
- Gen-ID
- 23633
- NCBI Accession
- NM_012316, NP_036448
- UniProt
- O60684
- Pathways
- Protein targeting to Nucleus
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