PHGDH Antikörper (Middle Region)

Produktnummer ABIN2785893

Der Kaninchen Polyklonal anti-PHGDH Antikörper wird verwendet zum Nachweis von PHGDH in Proben von Human, Maus, Ratte, Pferd, Schwein, Kaninchen und Hund. Er wurde validiert für WB.

Kurzübersicht für PHGDH Antikörper (Middle Region) (ABIN2785893)

Target: PHGDH (phosphoglycerate Dehydrogenase (PHGDH))

Reaktivität: Human, Maus, Ratte, Pferd, Schwein, Kaninchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHGDH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PHGDH Antikörper

Bindungsspezifität: Middle Region

Sequenz: SLKNAGNCLS PAVIVGLLKE ASKQADVNLV NAKLLVKEAG LNVTTSHSPA

Homologie: Dog: 92%, Horse: 83%, Human: 100%, Mouse: 100%, Pig: 86%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PHGDH. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PHGDH

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 533 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PHGDH

Target: PHGDH (phosphoglycerate Dehydrogenase (PHGDH))

Andere Bezeichnung: PHGDH

Hintergrund: 3-Phosphoglycerate dehydrogenase (PHGDH, EC 1.1.1.95) catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.3-Phosphoglycerate dehydrogenase (PHGDH, EC 1.1.1.95) catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.[supplied by OMIM].
Alias Symbols: 3-PGDH, 3PGDH, MGC3017, PDG, PGAD, PGD, PGDH, SERA
Protein Interaction Partner: HUWE1, UBC, FUS, SUMO2, ITSN1, ROM1, RPAP3, EPN1, SUMO1, NEDD8, MDM2, SUZ12, RNF2, EZH2, BMI1, FBXO6, TARDBP, EGFR, UBD, CLN5, CLN3, CDK2, PIAS4, FN1, TRAF3IP1, ECT2, MDC1, UQCC3, VASN, TRIM55, SMU1, TRA2A, ADNP, NCSTN, U2AF2, TCERG1, UTP14A, SRSF10, SAP1
Protein Size: 533

Molekulargewicht: 57 kDa

Gen-ID: 26227

NCBI Accession: NM_006623, NP_006614

UniProt: O08651

Pathways: Metabolism of Steroid Hormones and Vitamin D, Warburg Effekt