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Lactate Dehydrogenase A Antikörper (Middle Region)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Lactate Dehydrogenase A in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen, Hund, Ziege und Zebrafisch (Danio rerio) und wurde in 1 Publikation erwähnt.
Produktnummer ABIN2785876

Kurzübersicht für Lactate Dehydrogenase A Antikörper (Middle Region) (ABIN2785876)

Target

Alle Lactate Dehydrogenase A (LDHA) Antikörper anzeigen
Lactate Dehydrogenase A (LDHA)

Reaktivität

  • 85
  • 39
  • 30
  • 10
  • 6
  • 6
  • 5
  • 5
  • 5
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Human, Maus, Ratte, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen, Hund, Ziege, Zebrafisch (Danio rerio)

Wirt

  • 101
  • 21
  • 6
  • 5
Kaninchen

Klonalität

  • 108
  • 23
Polyklonal

Konjugat

  • 65
  • 21
  • 16
  • 9
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
Dieser Lactate Dehydrogenase A Antikörper ist unkonjugiert

Applikation

  • 97
  • 57
  • 46
  • 36
  • 32
  • 26
  • 10
  • 9
  • 6
  • 4
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 20
    • 9
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Sequenz

    PLSCHGWVLG EHGDSSVPVW SGMNVAGVSL KTLHPDLGTD KDKEQWKEVH

    Homologie

    Cow: 79%, Dog: 86%, Goat: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 79%, Zebrafish: 92%

    Produktmerkmale

    This is a rabbit polyclonal antibody against LDHA. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the middle region of human LDHA
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 332 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Listerman, Bledau, Grishina, Neugebauer: "Extragenic accumulation of RNA polymerase II enhances transcription by RNA polymerase III." in: PLoS genetics, Vol. 3, Issue 11, pp. e212, (2008) (PubMed).

  • Target

    Lactate Dehydrogenase A (LDHA)

    Andere Bezeichnung

    LDHA

    Hintergrund

    LDHA catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria.The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: LDH-M, LDH1, PIG19, LDHM, GSD11
    Protein Interaction Partner: MAPK10, LDHB, FUS, HUWE1, ISG15, UBC, SUMO2, SUMO3, STAU1, RPA3, RPA2, RPA1, ASB9, RNF2, CNDP2, NAGK, C11orf58, NDRG1, BZW1, KYNU, TCEA1, SORD, SMS, RPS6KA1, PGD, PAFAH1B3, GSR, PDIA3, GNAI3, DLD, CSE1L, LDHAL6B, FTO, BCCIP, XRN1, FBXO6, UPF2, YWHAQ, METT
    Protein Size: 332

    Molekulargewicht

    37 kDa

    Gen-ID

    3939

    NCBI Accession

    NM_005566, NP_005557

    UniProt

    P00338

    Pathways

    Warburg Effekt
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