GRK5 Antikörper (Middle Region)

Produktnummer ABIN2785866

Produktdetails anti-GRK5 Antikörper

Target: GRK5 (G Protein-Coupled Receptor Kinase 5 (GRK5))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Zebrafisch (Danio rerio), Kaninchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRK5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: FYAAEILCGL EDLHRENTVY RDLKPENILL DDYGHIRISD LGLAVKIPEG

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Yeast: 79%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against GRK5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GRK5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 590 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GRK5

Target: GRK5 (G Protein-Coupled Receptor Kinase 5 (GRK5))

Andere Bezeichnung: GRK5 (GRK5 Produkte)

Hintergrund: GRK5 is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs).This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GPRK5
Protein Interaction Partner: TBXA2R, USP47, C1QBP, YWHAB, XRCC5, UBTF, UBC, TUFM, NR2F1, TCOF1, SRPK1, SPTBN1, SPTAN1, SMARCA1, SKP1, SRSF1, RPL4, RPL3, RBMS1, PSMD11, PSMD2, PSMC6, PSMC2, PSMC1, PRKDC, PPP2R2A, PNN, PIP4K2A, PIP, NFIB, NCL, NCBP1, MYO9B, MYO1C, MYH10, MYH9, MYCN, MA
Protein Size: 590

Molekulargewicht: 68 kDa

Gen-ID: 2869

NCBI Accession: NM_005308, NP_005299

UniProt: P34947

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling