GRK5 Antikörper (Middle Region)

Produktnummer ABIN2785866

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GRK5 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Zebrafisch (Danio rerio), Kaninchen und Saccharomyces cerevisiae.

Kurzübersicht für GRK5 Antikörper (Middle Region) (ABIN2785866)

Target: GRK5 (G Protein-Coupled Receptor Kinase 5 (GRK5))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Zebrafisch (Danio rerio), Kaninchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRK5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-GRK5 Antikörper

Bindungsspezifität: Middle Region

Sequenz: FYAAEILCGL EDLHRENTVY RDLKPENILL DDYGHIRISD LGLAVKIPEG

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Yeast: 79%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against GRK5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GRK5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 590 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GRK5

Target: GRK5 (G Protein-Coupled Receptor Kinase 5 (GRK5))

Andere Bezeichnung: GRK5

Hintergrund: GRK5 is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs).This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GPRK5
Protein Interaction Partner: TBXA2R, USP47, C1QBP, YWHAB, XRCC5, UBTF, UBC, TUFM, NR2F1, TCOF1, SRPK1, SPTBN1, SPTAN1, SMARCA1, SKP1, SRSF1, RPL4, RPL3, RBMS1, PSMD11, PSMD2, PSMC6, PSMC2, PSMC1, PRKDC, PPP2R2A, PNN, PIP4K2A, PIP, NFIB, NCL, NCBP1, MYO9B, MYO1C, MYH10, MYH9, MYCN, MA
Protein Size: 590

Molekulargewicht: 68 kDa

Gen-ID: 2869

NCBI Accession: NM_005308, NP_005299

UniProt: P34947

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling