FTH1 Antikörper (N-Term)
Kurzübersicht für FTH1 Antikörper (N-Term) (ABIN2785802)
Target
Alle FTH1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
 - N-Term
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Sequenz
 - MTTASTSQVR QNYHQDSEAA INRQINLELY ASYVYLSMSY YFDRDDVALK
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Homologie
 - Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
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Produktmerkmale
 - This is a rabbit polyclonal antibody against FTH1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
 - Affinity Purified
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Immunogen
 - The immunogen is a synthetic peptide directed towards the N terminal region of human FTH1
 
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Applikationshinweise
 - Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 183 AA
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Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Format
 - Liquid
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Konzentration
 - Lot specific
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Buffer
 - Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
 - Sodium azide
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Vorsichtsmaßnahmen
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
 - Avoid repeated freeze-thaw cycles.
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Lagerung
 - -20 °C
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Informationen zur Lagerung
 - For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
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- FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))
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Andere Bezeichnung
 - FTH1
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Hintergrund
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                        FTH1 is the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. 
Alias Symbols: FTH, FTHL6, MGC104426, PIG15, PLIF, FHC
Protein Interaction Partner: SDCBP, FTL, FTH1, WDYHV1, CEP57, AURKB, TP53, AURKA, ASB15, ASB16, SUPT16H, SET, MAPK9, MAX, IGSF8, TICAM2, HCVgp1, PIAS4, CDC16, YWHAE, SOX5, MYL3, LBP, KPNA2, GRB2, DAXX, CSNK2B, CDC25A, ATP6V1B1, CD99, SPP1, TRAF4, SUMO2, UBC, Cep55, Trim28, NR1I3, NR3
Protein Size: 183 - 
                                            
Molekulargewicht
 - 21 kDa
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Gen-ID
 - 2495
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NCBI Accession
 - NM_002032, NP_002023
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UniProt
 - P02794
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Pathways
 - Transition Metal Ion Homeostasis
 
Target
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