FCN1 Antikörper (Middle Region)

Produktnummer ABIN2785793

Dieses Anti-FCN1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FCN1 in WB. Geeignet für Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Meerschweinchen und Schwein.

Kurzübersicht für FCN1 Antikörper (Middle Region) (ABIN2785793)

Target: FCN1 (Ficolin (Collagen/fibrinogen Domain Containing) 1 (FCN1))

Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FCN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FCN1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: GSQLGEFWLG NDNIHALTAQ GSSELRVDLV DFEGNHQFAK YKSFKVADEA

Homologie: Cow: 85%, Dog: 92%, Guinea Pig: 79%, Horse: 82%, Human: 100%, Mouse: 77%, Pig: 93%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against FCN1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FCN1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 326 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FCN1

Target: FCN1 (Ficolin (Collagen/fibrinogen Domain Containing) 1 (FCN1))

Andere Bezeichnung: FCN1

Hintergrund: The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1(FCN1) is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity.The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FCNM
Protein Interaction Partner: FCN1, TGFB1, ELN,
Protein Size: 326

Molekulargewicht: 32 kDa

Gen-ID: 2219

NCBI Accession: NM_002003, NP_001994

UniProt: O00602

Pathways: Komplementsystem