FRZB Antikörper (Middle Region)
Kurzübersicht für FRZB Antikörper (Middle Region) (ABIN2785778)
Target
Alle FRZB Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- VVEVKEILKS SLVNIPRDTV NLYTSSGCLC PPLNVNEEYI IMGYEDEERS
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Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%
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Produktmerkmale
- This is a rabbit polyclonal antibody against FRZB. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human FRZB
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 325 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FRZB (Frizzled-Related Protein (FRZB))
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Andere Bezeichnung
- FRZB
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Hintergrund
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The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility.
Alias Symbols: FRE, FRITZ, FRP-3, FRZB-1, FRZB-PEN, FRZB1, FZRB, SFRP3, SRFP3, hFIZ, OS1
Protein Interaction Partner: BBS10, PNO1, EHF, POLA2, RBX1, SMAD1, ELF5,
Protein Size: 325 -
Molekulargewicht
- 36 kDa
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Gen-ID
- 2487
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NCBI Accession
- NM_001463, NP_001454
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UniProt
- Q92765
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Pathways
- WNT Signalweg, Positive Regulation of fat Cell Differentiation
Target
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