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UBE4B Antikörper (N-Term)

Dieses Anti-UBE4B-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von UBE4B in WB. Geeignet für Human, Hund und Schwein.
Produktnummer ABIN2785770

Kurzübersicht für UBE4B Antikörper (N-Term) (ABIN2785770)

Target

Alle UBE4B Antikörper anzeigen
UBE4B (Ubiquitin Conjugation Factor E4 B (UBE4B))

Reaktivität

  • 35
  • 22
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Hund, Schwein

Wirt

  • 32
  • 3
Kaninchen

Klonalität

  • 30
  • 5
Polyklonal

Konjugat

  • 23
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser UBE4B Antikörper ist unkonjugiert

Applikation

  • 24
  • 13
  • 12
  • 5
  • 5
  • 4
  • 3
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    SPMFCSVASF GASSLSSLYE SSPAPTPSFW SSVPVMGPSL ASPSRAASQL

    Homologie

    Dog: 79%, Human: 100%, Pig: 79%

    Produktmerkmale

    This is a rabbit polyclonal antibody against UBE4B. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human UBE4B
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 1302 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    UBE4B (Ubiquitin Conjugation Factor E4 B (UBE4B))

    Andere Bezeichnung

    UBE4B

    Hintergrund

    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B is an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. The gene that encodes the protein is also the strongest candidate in the neuroblastoma tumor suppressor genes. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
    Alias Symbols: E4, HDNB1, KIAA0684, UBOX3, UFD2, UFD2A
    Protein Interaction Partner: TRIP12, UBC, FBXW11, HGS, STAM, TP53, MDM2, NUSAP1, NUDCD3, RBM12, PDE3A, CDKN2A, UBL7, UBE2D3, CDC27, TTK, IGBP1, HDLBP, TTC9C, MRPL53, ZFYVE19, SARNP, SRPRB, VPS35, UBA6, VPS29, UFM1, SBDS, VPS36, UBQLN1, UBXN7, UBE2C, AHCYL1, SSSCA1, SF3B4, PPIF, SCO2,
    Protein Size: 1302

    Molekulargewicht

    146 kDa

    Gen-ID

    10277

    NCBI Accession

    NM_001105562, NP_001099032

    UniProt

    O95155
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