IGF2 Antikörper (C-Term)

Produktnummer ABIN2785661

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IGF2 in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus, Rind (Kuh), Hund, Pferd, Schwein, Ziege und Schaf.

Kurzübersicht für IGF2 Antikörper (C-Term) (ABIN2785661)

Target: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Pferd, Schwein, Ziege, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IGF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IGF2 Antikörper

Bindungsspezifität: C-Term

Sequenz: YDTWKQSTQR LRRGLPALLR ARRGHVLAKE LEAFREAKRH RPLIALPTQD

Homologie: Cow: 93%, Dog: 93%, Goat: 93%, Horse: 86%, Human: 100%, Mouse: 92%, Pig: 85%, Rat: 92%, Sheep: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against IGF2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 236 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IGF2

Target: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Andere Bezeichnung: IGF2

Hintergrund: This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: C11orf43, FLJ22066, FLJ44734, INSIGF, pp9974, IGF-II, PP9974
Protein Interaction Partner: RBPMS, PCSK4, NMRK2, FAF1, BAG6, IGFBP7, GPC3, VTN, PLG, NOV, INSR, IGF1R, IGF2R, IGFBP6, IGFBP5, IGFBP4, IGFBP3, IGFBP2, IGFBP1, IDE, TF,
Protein Size: 236

Molekulargewicht: 25 kDa

Gen-ID: 3481

NCBI Accession: NM_001127598, NP_001121070

UniProt: C9JAF2

Pathways: Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation