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Aminomethyltransferase Antikörper (N-Term)

Der Kaninchen Polyklonal Anti-Aminomethyltransferase-Antikörper wurde für WB validiert. Er ist geeignet, Aminomethyltransferase in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio) zu detektieren.
Produktnummer ABIN2785650

Kurzübersicht für Aminomethyltransferase Antikörper (N-Term) (ABIN2785650)

Target

Alle Aminomethyltransferase (AMT) Antikörper anzeigen
Aminomethyltransferase (AMT)

Reaktivität

  • 25
  • 7
  • 6
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt

  • 21
  • 4
Kaninchen

Klonalität

  • 23
  • 2
Polyklonal

Konjugat

  • 21
  • 2
  • 1
  • 1
Dieser Aminomethyltransferase Antikörper ist unkonjugiert

Applikation

  • 20
  • 9
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    N-Term

    Sequenz

    QRAVSVVARL GFRLQAFPPA LCRPLSCAQE VLRRTPLYDF HLAHGGKMVA

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

    Produktmerkmale

    This is a rabbit polyclonal antibody against AMT. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human AMT
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 403 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    Aminomethyltransferase (AMT)

    Andere Bezeichnung

    AMT

    Hintergrund

    The enzyme system for cleavage of glycine (glycine cleavage system, EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). Glycine encephalopathy (GCE) may be due to a defect in any one of these enzymes.The enzyme system for cleavage of glycine (glycine cleavage system, EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase, MIM 238300), H protein (a lipoic acid-containing protein, MIM 238330), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase, MIM 238331). Glycine encephalopathy (GCE, MIM 605899) may be due to a defect in any one of these enzymes.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2102 D13811.1 1-2102 2103-2117 BC044792.1 3271-3285
    Alias Symbols: GCE, GCST, NKH, GCVT
    Protein Interaction Partner: HSPA8,
    Protein Size: 403

    Molekulargewicht

    44 kDa

    Gen-ID

    275

    NCBI Accession

    NM_000481, NP_000472

    UniProt

    P48728
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