LIG1 Antikörper (Middle Region)
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- Target Alle LIG1 Antikörper anzeigen
- LIG1 (Ligase I, DNA, ATP-Dependent (LIG1))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Ratte, Maus, Rind (Kuh), Kaninchen, Hund, Pferd, Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser LIG1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- PSVTSFILDT EAVAWDREKK QIQPFQVLTT RKRKEVDASE IQVQVCLYAF
- Homologie
- Cow: 92%, Dog: 92%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 85%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against LIG1. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human LIG1
- Top Product
- Discover our top product LIG1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 919 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- LIG1 (Ligase I, DNA, ATP-Dependent (LIG1))
- Andere Bezeichnung
- LIG1 (LIG1 Produkte)
- Hintergrund
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LIG1is DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents.
Alias Symbols: MGC117397, MGC130025
Protein Interaction Partner: PCNA, UBC, PRMT3, SUMO2, RGS2, TUBB3, MRE11A, INPP1, CSNK2A1,
Protein Size: 919 - Molekulargewicht
- 102 kDa
- Gen-ID
- 3978
- NCBI Accession
- NM_000234, NP_000225
- UniProt
- P18858
- Pathways
- Telomere Maintenance, DNA Reparatur, DNA Replication, Synthesis of DNA
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