LIG1 Antikörper (Middle Region)
Kurzübersicht für LIG1 Antikörper (Middle Region) (ABIN2785647)
Target
Alle LIG1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- PSVTSFILDT EAVAWDREKK QIQPFQVLTT RKRKEVDASE IQVQVCLYAF
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Homologie
- Cow: 92%, Dog: 92%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 85%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against LIG1. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human LIG1
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 919 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- LIG1 (Ligase I, DNA, ATP-Dependent (LIG1))
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Andere Bezeichnung
- LIG1
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Hintergrund
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LIG1is DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents.
Alias Symbols: MGC117397, MGC130025
Protein Interaction Partner: PCNA, UBC, PRMT3, SUMO2, RGS2, TUBB3, MRE11A, INPP1, CSNK2A1,
Protein Size: 919 -
Molekulargewicht
- 102 kDa
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Gen-ID
- 3978
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NCBI Accession
- NM_000234, NP_000225
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UniProt
- P18858
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Pathways
- Telomere Maintenance, DNA Reparatur, DNA Replication, Synthesis of DNA
Target
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