LIG1 Antikörper (Middle Region)

Produktnummer ABIN2785646

Produktdetails anti-LIG1 Antikörper

Target: LIG1 (Ligase I, DNA, ATP-Dependent (LIG1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Kaninchen, Hund, Pferd, Meerschweinchen, Ziege, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LIG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ALEGGEVKIF SRNQEDNTGK YPDIISRIPK IKLPSVTSFI LDTEAVAWDR

Homologie: Cow: 93%, Dog: 100%, Goat: 79%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against LIG1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LIG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 919 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu LIG1

Target: LIG1 (Ligase I, DNA, ATP-Dependent (LIG1))

Andere Bezeichnung: LIG1 (LIG1 Produkte)

Synonyme: ATLIG1 antikoerper, DNA ligase 1 antikoerper, T6D22.23 antikoerper, ligI antikoerper, AL033288 antikoerper, LigI antikoerper, lig1 antikoerper, wu:fc54a11 antikoerper, DNA ligase 1 antikoerper, DNA ligase 1, putative antikoerper, ligase I, DNA, ATP-dependent L homeolog antikoerper, ligase I, DNA, ATP-dependent antikoerper, LIG1 antikoerper, PB000674.02.0 antikoerper, PTRG_06243 antikoerper, PKH_140260 antikoerper, lig1.L antikoerper, Lig1 antikoerper, lig-1 antikoerper, lig1 antikoerper

Hintergrund: LIG1is DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents.LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC117397, MGC130025
Protein Interaction Partner: PCNA, UBC, PRMT3, SUMO2, RGS2, TUBB3, MRE11A, INPP1, CSNK2A1,
Protein Size: 919

Molekulargewicht: 102 kDa

Gen-ID: 3978

NCBI Accession: NM_000234, NP_000225

UniProt: P18858

Pathways: Telomere Maintenance, DNA Reparatur, DNA Replication, Synthesis of DNA