GLA Antikörper (N-Term)

Produktnummer ABIN2785641

Produktdetails anti-GLA Antikörper

Target: GLA (Galactosidase, alpha (GLA))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Rind (Kuh), Ziege, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PQRFPHGIRQ LANYVHSKGL KLGIYADVGN KTCAGFPGSF GYYDIDAQTF

Homologie: Cow: 93%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against GLA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GLA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 429 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GLA

Target: GLA (Galactosidase, alpha (GLA))

Andere Bezeichnung: GLA (GLA Produkte)

Synonyme: GALA antikoerper, Ags antikoerper, zgc:101584 antikoerper, MGC130872 antikoerper, SMU.877 antikoerper, SCF11.21 antikoerper, AO090005000217 antikoerper, alpha-GAL antikoerper, galactosidase alpha antikoerper, galactosidase, alpha antikoerper, galactosidase alpha S homeolog antikoerper, alpha-galactosidase antikoerper, aga antikoerper, alpha-galactosidase A antikoerper, GLA antikoerper, Gla antikoerper, gla antikoerper, gla.S antikoerper, agaN antikoerper, aga antikoerper, agaL antikoerper, SCO0541 antikoerper, rafA antikoerper, melA antikoerper, galA antikoerper, ANI_1_2528074 antikoerper, ANI_1_1502124 antikoerper, AOR_1_390174 antikoerper, CpipJ_CPIJ002066 antikoerper, MCYG_00962 antikoerper, MCYG_00791 antikoerper, Tsp_02909 antikoerper, Tsp_02508 antikoerper

Hintergrund: GLA is a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GALA
Protein Interaction Partner: ZNF622, CNDP2, MAT2B, EIF4H, PGD, GNS, GBP2, G6PD, EIF5, CAPN1, ALDH7A1, TERT, UBC, FBXO6, OTUD4, GLA,
Protein Size: 429

Molekulargewicht: 45 kDa

Gen-ID: 2717

NCBI Accession: NM_000169, NP_000160

UniProt: P06280

Pathways: SARS-CoV-2 Protein Interaktom