GLA Antikörper (N-Term)

Produktnummer ABIN2785641

Der Kaninchen Polyklonal anti-GLA Antikörper wird verwendet zum Nachweis von GLA in Proben von Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Rind (Kuh), Ziege, Kaninchen und Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für GLA Antikörper (N-Term) (ABIN2785641)

Target: GLA (Galactosidase, alpha (GLA))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Rind (Kuh), Ziege, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GLA Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: GLA Antibody - N-terminal region

Sequenz: PQRFPHGIRQ LANYVHSKGL KLGIYADVGN KTCAGFPGSF GYYDIDAQTF

Homologie: Cow: 93%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against GLA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GLA

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54296-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu GLA

Target: GLA (Galactosidase, alpha (GLA))

Andere Bezeichnung: GLA

Hintergrund:

Background Information: GLA is a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Galactosidase, alpha

Alternative Symbols: GALA

Protein Name: Alpha-galactosidase A

Molekulargewicht: 49 kDa

Gen-ID: 2717

NCBI Accession: NP_000160

UniProt: P06280

Pathways: SARS-CoV-2 Protein Interaktom