ATG10 Antikörper (C-Term)
Kurzübersicht für ATG10 Antikörper (C-Term) (ABIN2785625)
Target
Alle ATG10 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- TPVLKNSQKI NKNVNYITSW LSIVGPVVGL NLPLSYAKAT SQDERNVP
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Homologie
- Cow: 86%, Dog: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against ATG10. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human ATG10
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 220 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ATG10 (Autophagy Related 10 (ATG10))
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Andere Bezeichnung
- ATG10
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Hintergrund
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Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12-ATG5 conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A), a homolog of yeast Apg8, to a membrane-bound form.Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A, MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM].
Alias Symbols: APG10, APG10L, DKFZP586I0418, FLJ13954, pp12616
Protein Interaction Partner: ATG3, ATG4B, ATG7, HAT1, USP11, USP7, RBBP7, MAP1B, KRT85, ADSS, ATG5, ATG12,
Protein Size: 220 -
Molekulargewicht
- 25 kDa
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Gen-ID
- 83734
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NCBI Accession
- NM_031482, NP_113670
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UniProt
- Q9H0Y0
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Pathways
- ER-Nucleus Signaling, Autophagie
Target
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