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ATG10 Antikörper (C-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ATG10 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen und Pferd.
Produktnummer ABIN2785625

Kurzübersicht für ATG10 Antikörper (C-Term) (ABIN2785625)

Target

Alle ATG10 Antikörper anzeigen
ATG10 (Autophagy Related 10 (ATG10))

Reaktivität

  • 61
  • 14
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd

Wirt

  • 59
  • 1
  • 1
Kaninchen

Klonalität

  • 58
  • 3
Polyklonal

Konjugat

  • 27
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ATG10 Antikörper ist unkonjugiert

Applikation

  • 25
  • 22
  • 20
  • 13
  • 13
  • 8
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 15
    • 8
    • 8
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    C-Term

    Sequenz

    TPVLKNSQKI NKNVNYITSW LSIVGPVVGL NLPLSYAKAT SQDERNVP

    Homologie

    Cow: 86%, Dog: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against ATG10. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the C terminal region of human ATG10
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 220 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    ATG10 (Autophagy Related 10 (ATG10))

    Andere Bezeichnung

    ATG10

    Hintergrund

    Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12-ATG5 conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A), a homolog of yeast Apg8, to a membrane-bound form.Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A, MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM].
    Alias Symbols: APG10, APG10L, DKFZP586I0418, FLJ13954, pp12616
    Protein Interaction Partner: ATG3, ATG4B, ATG7, HAT1, USP11, USP7, RBBP7, MAP1B, KRT85, ADSS, ATG5, ATG12,
    Protein Size: 220

    Molekulargewicht

    25 kDa

    Gen-ID

    83734

    NCBI Accession

    NM_031482, NP_113670

    UniProt

    Q9H0Y0

    Pathways

    ER-Nucleus Signaling, Autophagie
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