Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch APH1B in WB. Er zeigt eine Reaktivität gegenüber Maus, Human, Ratte, Kaninchen, Rind (Kuh), Hund und Meerschweinchen.
Aph1b
Reaktivität: Maus
WB, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 647
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeat freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target
APH1B (Aph1b)
(Anterior Pharynx Defective 1 Homolog B (Aph1b))
Andere Bezeichnung
APH1B
Hintergrund
This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein. Alias Symbols: APH-1B, PRO1328, PSFL, TAAV688 Protein Interaction Partner: UBC, PSENEN, NCSTN, PSEN2, PSEN1, Protein Size: 257