APH1B Antikörper (N-Term)

Produktnummer ABIN2785589

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch APH1B in WB. Es zeigt Reaktivität gegenüber Proben von Maus, Human, Ratte, Kaninchen, Rind (Kuh), Hund und Meerschweinchen.

Kurzübersicht für APH1B Antikörper (N-Term) (ABIN2785589)

Target: APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))

Reaktivität: Maus, Human, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APH1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-APH1B Antikörper

Bindungsspezifität: N-Term

Sequenz: IIDNKDGPTQ KYLLIFGAFV SVYIQEMFRF AYYKLLKKAS EGLKSINPGE

Homologie: Cow: 92%, Dog: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against APH1B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human APH1B

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu APH1B

Target: APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))

Andere Bezeichnung: APH1B

Hintergrund: This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein.
Alias Symbols: APH-1B, PRO1328, PSFL, TAAV688
Protein Interaction Partner: UBC, PSENEN, NCSTN, PSEN2, PSEN1,
Protein Size: 257

Molekulargewicht: 28 kDa

Gen-ID: 83464

NCBI Accession: NM_031301, NP_112591

UniProt: Q8WW43

Pathways: Notch Signalweg, Neurotrophin Signalübertragung