Inhibin alpha Antikörper (N-Term)
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- Target Alle Inhibin alpha (INHA) Antikörper anzeigen
- Inhibin alpha (INHA) (Inhibin, alpha (INHA))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Maus, Ratte, Schwein, Rind (Kuh), Schaf, Kaninchen, Hund, Ziege, Pferd, Saccharomyces cerevisiae
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Inhibin alpha Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- GLAQEAEEGL FRYMFRPSQH TRSRQVTSAQ LWFHTGLDRQ GTAASNSSEP
- Homologie
- Cow: 100%, Dog: 86%, Goat: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 79%, Rat: 93%, Sheep: 100%, Yeast: 79%
- Produktmerkmale
- This is a rabbit polyclonal antibody against INHA. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human INHA
- Top Product
- Discover our top product INHA Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 366 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Inhibin alpha (INHA) (Inhibin, alpha (INHA))
- Andere Bezeichnung
- INHA (INHA Produkte)
- Synonyme
- si:dkey-91f15.2 antikoerper, INHA antikoerper, MGC108500 antikoerper, AW555078 antikoerper, inhibin, alpha antikoerper, inhibin alpha subunit antikoerper, inhibin alpha antikoerper, inhibin alpha L homeolog antikoerper, inha antikoerper, INHA antikoerper, inha.L antikoerper, Inha antikoerper
- Hintergrund
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INHA joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: SIAH1, TGFBR3, INHBB, INHBA, FST, ACVR2A,
Protein Size: 366 - Molekulargewicht
- 40 kDa
- Gen-ID
- 3623
- NCBI Accession
- NM_002191, NP_002182
- UniProt
- P05111
- Pathways
- Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion
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