AP2B1 Antikörper (C-Term)

Produktnummer ABIN2785455

Dieses Anti-AP2B1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von AP2B1 in WB. Geeignet für Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio). Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für AP2B1 Antikörper (C-Term) (ABIN2785455)

Target: AP2B1 (Adaptor-Related Protein Complex 2, beta 1 Subunit (AP2B1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AP2B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-AP2B1 Antikörper

Bindungsspezifität: C-Term

Sequenz: GAVDLLGGGL DSLLGSDLGG GIGGSPAVGQ SFIPSSVPAT FAPSPTPAVV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against AP2B1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human AP2B1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 951 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-AP2B1 Antikörper (ABIN2785455)

Schmid, Ford, Burtey, Praefcke, Peak-Chew, Mills, Benmerah, McMahon: "Role of the AP2 beta-appendage hub in recruiting partners for clathrin-coated vesicle assembly." in: PLoS biology, Vol. 4, Issue 9, pp. e262, (2006) (PubMed).

Details zu AP2B1

Target: AP2B1 (Adaptor-Related Protein Complex 2, beta 1 Subunit (AP2B1))

Andere Bezeichnung: AP2B1

Hintergrund: AP2B1 is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. AP2B1 is found on the cytoplasmic face of coated vesicles in the plasma membrane.The protein encoded by this gene is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ADTB2, AP105B, AP2-BETA, CLAPB1, DKFZp781K0743
Protein Interaction Partner: NEU4, XRCC6BP1, THAP1, U2AF1, KPNA2, SLC25A6, AFF4, TXN2, PIP5K1C, RAPGEF3, AP1M2, SUMO2, GTF2I, UBC, EGFR, SUMO1, NEDD8, EPHA2, RPA3, RPA2, RPA1, SEC24C, NUSAP1, EPN1, XPO7, PLOD2, LNPEP, GRB2, LDLRAP1, AP2M1, UBD, RNF11, MMS19, ITGA4, FN1, ERBB2, DAB2,
Protein Size: 951

Molekulargewicht: 105 kDa

Gen-ID: 163

NCBI Accession: NM_001030006, NP_001025177

UniProt: P63010

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, EGFR Downregulation