Ensa Antikörper (N-Term)

Produktnummer ABIN2785426

Dieses Anti-Ensa-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Ensa in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein und Kaninchen.

Kurzübersicht für Ensa Antikörper (N-Term) (ABIN2785426)

Target: Ensa (ENSA) (Endosulfine alpha (ENSA))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ensa Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Ensa Antikörper

Bindungsspezifität: N-Term

Sequenz: MAGGLGCDVC YWFVEDTQEK EGILPERAEE AKLKAKYPSL GQKPGGSDFL

Homologie: Cow: 92%, Dog: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Pig: 92%, Rabbit: 92%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against ENSA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ENSA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 113 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Ensa

Target: Ensa (ENSA) (Endosulfine alpha (ENSA))

Andere Bezeichnung: ENSA

Hintergrund: The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alias Symbols: MGC4319, MGC78563, MGC8394, ARPP-19e
Protein Interaction Partner: UBC, SNCA, PSEN1, ACD, POT1, RAP2A, RIM15, KCTD15, ARIH2, ABCC8, ENO2, MCM3,
Protein Size: 113

Molekulargewicht: 12 kDa

Gen-ID: 2029

NCBI Accession: NM_207047, NP_996930

UniProt: O43768