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DNAJC24 Antikörper (N-Term)

Dieser Anti-DNAJC24 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von DNAJC24 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen und Kaninchen.
Produktnummer ABIN2785377

Kurzübersicht für DNAJC24 Antikörper (N-Term) (ABIN2785377)

Target

Alle DNAJC24 Antikörper anzeigen
DNAJC24 (DnaJ (Hsp40) Homolog, Subfamily C, Member 24 (DNAJC24))

Reaktivität

Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen

Wirt

  • 15
Kaninchen

Klonalität

  • 15
Polyklonal

Konjugat

  • 10
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser DNAJC24 Antikörper ist unkonjugiert

Applikation

  • 14
  • 10
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 8
    • 2
    • 2
    • 2
    • 2
    • 1
    N-Term

    Sequenz

    MMAVEQMPKK DWYSILGADP SANISDLKQK YQKLILMYHP DKQSTDVPAG

    Homologie

    Cow: 86%, Dog: 86%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 86%

    Produktmerkmale

    This is a rabbit polyclonal antibody against DPH4. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human DPH4
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 149 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    DNAJC24 (DnaJ (Hsp40) Homolog, Subfamily C, Member 24 (DNAJC24))

    Andere Bezeichnung

    DPH4

    Hintergrund

    Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2.Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-10 CD685768.1 19-28 11-652 AL833128.1 1-642 653-3000 AC108456.7 42515-44862
    Alias Symbols: JJJ3, ZCSL3, DPH4
    Protein Size: 149

    Molekulargewicht

    17 kDa

    Gen-ID

    120526

    NCBI Accession

    NM_181706, NP_859057

    UniProt

    Q6P3W2
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