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DNAJC24 Antikörper (N-Term)

Dieses Anti-DNAJC24-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DNAJC24 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen und Kaninchen.
Produktnummer ABIN2785377

Kurzübersicht für DNAJC24 Antikörper (N-Term) (ABIN2785377)

Target

Alle DNAJC24 Antikörper anzeigen
DNAJC24 (DnaJ (Hsp40) Homolog, Subfamily C, Member 24 (DNAJC24))

Reaktivität

Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen

Wirt

  • 16
Kaninchen

Klonalität

  • 16
Polyklonal

Konjugat

  • 11
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser DNAJC24 Antikörper ist unkonjugiert

Applikation

  • 15
  • 10
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 8
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    N-Term

    Sequenz

    MMAVEQMPKK DWYSILGADP SANISDLKQK YQKLILMYHP DKQSTDVPAG

    Homologie

    Cow: 86%, Dog: 86%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 86%

    Produktmerkmale

    This is a rabbit polyclonal antibody against DPH4. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human DPH4
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 149 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    DNAJC24 (DnaJ (Hsp40) Homolog, Subfamily C, Member 24 (DNAJC24))

    Andere Bezeichnung

    DPH4

    Hintergrund

    Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2.Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-10 CD685768.1 19-28 11-652 AL833128.1 1-642 653-3000 AC108456.7 42515-44862
    Alias Symbols: JJJ3, ZCSL3, DPH4
    Protein Size: 149

    Molekulargewicht

    17 kDa

    Gen-ID

    120526

    NCBI Accession

    NM_181706, NP_859057

    UniProt

    Q6P3W2
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