LRRC50 Antikörper (N-Term)

Produktnummer ABIN2785360

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch LRRC50 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd und Zebrafisch (Danio rerio). Es wurde in 3+ Publikationen zitiert.

Kurzübersicht für LRRC50 Antikörper (N-Term) (ABIN2785360)

Target: LRRC50 (Leucine Rich Repeat Containing 50 (LRRC50))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRRC50 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-LRRC50 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: LRRC50 Antibody - N-terminal region

Sequenz: LNDTLYLHFK GFDRIENLEE YTGLRCLWLQ SNGIQKIENL EAQTELRCLF

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against LRRC50. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LRRC50

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53358-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-LRRC50 Antikörper (ABIN2785360)

Basten, Davis, Gillis, van Rooijen, Stoop, Babala, Logister, Heath, Jonges, Katsanis, Voest, van Eeden, Medema, Ketting, Schulte-Merker, Looijenga, Giles: "Mutations in LRRC50 predispose zebrafish and humans to seminomas." in: PLoS genetics, Vol. 9, Issue 4, pp. e1003384, (2013) (PubMed).

Yang, Zhou, Ma, Wang, Chen, Meng, Yu, Zhou, Sun: "Knockdown of PPAR δ gene promotes the growth of colon cancer and reduces the sensitivity to bevacizumab in nude mice model." in: PLoS ONE, Vol. 8, Issue 4, pp. e60715, (2013) (PubMed).

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Details zu LRRC50

Target: LRRC50 (Leucine Rich Repeat Containing 50 (LRRC50))

Andere Bezeichnung: LRRC50

Hintergrund:

Background Information: LRRC50 contains 6 LRR (leucine-rich) repeats. It is proposed that LRRC50 to be a novel candidate gene for human cystic kidney disease, involved in regulation of microtubule-based cilia and actin-based brush border microvilli.

Gene Name: Dynein, axonemal, assembly factor 1

Alternative Symbols: swt, DAU1, ODA7, CILD13, LRRC50

Protein Name: Dynein assembly factor 1, axonemal

Molekulargewicht: 80kDa

Gen-ID: 123872

NCBI Accession: NP_848547

UniProt: Q8NEP3